Non-Hodgkin’s lymphoma is a cancer that emerges from the lymphatic system. This system is the disease-fighting network that runs through the body. In this type of cancer, tumors develop from lymphocytes, which are a type of white blood cell. Non-Hodgkin’s lymphoma is more common than Hodgkin lymphoma. When these cells start to become cancerous, the body gets affected by lymphoma. The causes and risk factors of non-Hodgkin’s lymphoma include the following:
1. Causes of non-Hodgkin’s Lymphoma
The main cause of non-Hodgkin’s lymphoma can be attributed to a mutation in a white blood cell known as a lymphocyte. However, the exact cause of this is still relatively unknown.
Moreover, to understand the causes of non-Hodgkin’s lymphoma better, it is important to figure out the working of DNA. A strand of DNA gives our cells fundamental instructions. These instructions consist of when to grow and when to reproduce.
When a mutation occurs in the DNA, it can force it to change the basic instructions. So, these cells will keep on growing uncontrollably. The abnormal types of lymphocytes then start multiplying in more than one lymph node in the body. This can occur in the neck, groins, or even the armpit. As time passes, the abnormal lymphocytes can keep spreading. They may further spread to the spleen, liver, lungs, skin, brain, stomach, and bone marrow.
However, in some cases, non-Hodgkin’s lymphoma mutations may start growing in an organ itself. It will start with a lymph node and then further go into the organ. Hence, it is crucial to recognize the risk factors and get regular check-ups done to keep this problem at bay.
2. Risk factors of non-Hodgkin’s lymphoma
Some people fall into a higher risk bracket for this cancer due to the following factors:
NHL is most commonly found in seniors who are 60 years and above. Hence, an older person is likely to face a higher risk of getting this disorder.
As per a number of studies, people of African-American descent are more prone to developing NHL. The second group that is also highly susceptible to getting this type of cancer is Asian-Americans.
NHL is more commonly found in males. However, there are certain subtypes of NHL that are more frequently found in women.
For people who have close relatives suffering from NHL, the chances of getting this disorder increase manifold.
Some studies reflect that there are certain drugs and substances that may increase your risk of getting NHL. For example, certain herbicides or benzene can be attributed to a much higher risk of NHL.
People may have a weak immune system due to many reasons. For example, right after an organ transplant, the immunity of the patient gets compromised. Genetic disorders that affect the immune system may increase your chances of getting NHL as well. People with HIV are also vulnerable.
Now that you are aware of the risk factors and causes of non-Hodgkin’s lymphoma, it is advisable to get regular screenings done. Always seek timely treatment to ensure the best chances of recovery.
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